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减肥期间可以吃酸奶吗

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达美航空货运部副总裁科尔表示,我们正在积极寻求为客户提供新的供应链解决方案,这同样也为企业突出重围提供了一个新的机会国际航协的评估认为,当前航空企业面临的最大困难是缺乏稳定的现金流根据最新数据显示,75%的航企手头现金不足以负担今后3个月不可避免的固定成本开支会上,学院党委副书记丁志强强调,班主任考核工作不仅仅是一次考核,更是一个总结提高的过程考核的目的在于提高,通过考核,总结班主任工作成效和经验,查摆问题,整改提高,进一步提升班主任服务学生工作能力和水平,充分调动班主任工作的积极性、主动性、创造性,促进班主任工作的制度化、规范化同时希望考核工作领导小组成员老师严格按照学校《安徽理工大学班主任工作条例》、《关于做好2012级班主任考核工作的通知》、《土木建筑学院班主任工作考核办法(试行)》等文件精神和要求,实事求是,严格标准,按时完成学院班主任考核土木建筑学院党委召开新学期第一次党支部书记例会9月6日上午,土木建筑学院党委召开新学期第一次党支部书记例会院党委书记盛真、党委副书记丁志强,各党支部书记参加了会议

我们第一次以lettertotheeditor的格式投molecularpsychiatry,精神病学的旗舰杂志,审稿50天(9月22日-11月12日),拒稿,两个审稿人的意见如下: Reviewer#1(CommentstotheAuthor): Thisreportofnoassociationofrs1234inchinaiscredible,althoughIfindthefinalrecommendationlessso.IfitisassociatedwithendophenotypesthataretrueintermediatephenotypesforSZ,thenthefailuretofindassociationtoSZbecomessimplyoneofpower.Sothefinalconclusionscontradicttheprimaryconclusions.Ithinktheprimaryconclusionismorestronglysupported. Metaanalysesonthescaleconductedarefairlytrivial.Iwouldnotthinkmolecularpsychiatryisthecorrectplaceforthem. Reviewer#2(CommentstotheAuthor): Thismanuscriptdescribesameta-analysisofrs1234inChinesesamples.ThemarkerwasreportedtobeassociatedwithschizophreniainEuropeanpopulationsinalargeassociationstudy.Overall,themethodusedinthispaperisappropriate,butIfeelthattheauthorsmighthaveover-interpretedtheirresults.Theappropriateconclusionisthattheanalysisdidnotprovideclearevidence,onewayortheother.Thereasonsarebelow: 1.Inassociationstudies,areplicationstudynormallyrequiresmuchlargersamplesize.Inthiscase,theoriginalstudywasdonewith7,308casesand12,834controls,thereportedORis1.12.Thismetaanalysiscollectedasampleof8,460casesand11,549controls.Giventhewinner'scurse,wewouldexpectasmallereffectsize,therefore,foradirectreplication,thissamplesizeismarginal,asshownintheirownpowercalculationwithanORof1.1.IfweusetheactualORof1.06todothecalculation,thepowermaybelessthan80%. 2.Forthisanalysis,itisatestifAalleleisariskfactorforschizophrenia,soitcanbeinterpretedasaone-tailedtest.Underthiscircumstance,apvalueof0.12canbeinterpretedassignificant,supportingtheassociationofAallelewiththerisktoschizophrenia.Whilethisinterpretationmaybeliberal,interpretingthisasevidenceofnoassociationisalsoproblematic. Aminorissueistheuseofimagedata.Ithinkitisunnecessaryinthismanuscript.AnegativeassociationofthisSNPwiththosebrainstructuralphenotypesshouldnotbeinterpretedasnoassociationofthemarkerwiththedisease,orviceversa. 这次投稿的时候在meta-analysis还包括了brainimaging的data,但是两个审稿人的意见并不positive,因此主编拒稿,也在我们的情理之中,后来我们又将该文章扩写成article,改投到schizophreniabulletin,审稿26天(11月19日-12月15日),拒稿,审稿人的意见如下: Referee:1-----CommentstotheAuthor InthisstudytheauthorsexaminetheeffectoftheputativeschizophreniariskSNPrs1234,byameta-analysisofpreviousstudiesinChinese.TheyfurtheralsostudytheeffectofthisSNPonbrainstructuresinhealthyChinesesubjects. ThestudyofriskvariantsforschizophreniainpopulationsotherthanthatofWesternEuropeandecentisveryimportantandinteresting,andthemethodologyofthepaperseemssound. However,mymajorconcernisthatinmyopinionthepresentpaperdoesnotaddenoughtowhatiscurrentlyalreadyknownaboutthesubject(andforexamplepresentedintheindividualstudiesthatarepartofthemeta-analysis).Theadditionalanalysisofbrainstructuresalsoseemsabit"forced",asthisanalysiswasonlyperformedonhealthycontrols,notonpatientswithschizophrenia.Inpreviousstudies,effectsofrs1234on(functioningofthebrain)weresometimespresentinschizophreniapatientswhileabsentinhealthycontrols. Othermoreminorconcerns: -Spellingandgrammarissometimespoorandthisshouldbecorrected. -Theauthorsshouldgointoabitmoredetailintheanalysisofbrainstructurs,forexampleintheresultssection.Itwouldalsobemorecorrecttospeakof"associationwithvolumesofbrainstructures"insteadof"associationwithbrainstructures". -Thetitledoesnotreflectthebrainstructureanalysis,asthisanalysishasnothingtodowithrs1234andschizophreniariskinChinese. -Attheend(page25),aftertheSupplementaryMaterial,thereisasecondlistofReferences.Thisseemstobeamistake,asthereferencesarenotcorrespondingtotherightnumbersinthemanusciptortheSupplementaryMaterial. Referee:2-----CommentstotheAuthor Thearticledescribedameta-analaysisofrs1234associationwithschizophreniainChinesesamples.Withareasonablecombinedsamplesize,theanalysisdidnotfindevidencetosupporttheassociation.Asacknowledgedbytheauthors,thesamplesizewasunderpoweredgiventheobservedOR.Basedontheseanalyses,Iwouldsuggestthattheauthorsrevisetheirconclusionto"collectively,thisanalysisdidnotfindevidence...",becausethelackofassociationmaybeduetothesamplesize,andfurtheranalysesmaybenecessary. Minorsuggestions: 1.ThediscussionofCMYA5andothergenesisnotrelevanttothisarticle,becauseasmallerorlargerORataunlinkedlocushasnobearingonthisSNP. 2.Pleasedroptheword"strong"inthedescriptionofassociation,sinceanORof~1.1isnotreallystrong. 根据第一个审稿人的意见,我们在文章中细致的描述了纳入的样本的特征(包括年龄、性别比例等),并加入了一些meta-analysis的必要分析,另外,我们将brainimagingdata从文章中移除,该文章彻底变成了一篇meta-analysis,随后又将文章改投到biologicalpsychiatry,审稿40天(12月19日-1月29日),拒稿,三个审稿人的意见如下: Reviewer#1:Inthisstudy,theauthorsconductedextensivemeta-analysisofschizophreniaassociationstudiesinChinesepopulationsforSNPrs1234.Theydidnotshowanoverallsignificantassociation.Thisisanimportantnegativestudy,showingthatdespitenumerousreplicationsinEuropeanpopulation,thisSNPdoesnotappeartoincreaseriskforschizophreniainChinesepeople.Thestudyiswelldoneandveryclearlywritten.Thenumberofsubjectsincludedinthismeta-analysisislarge(total~20,000),andthenumberofstudiesexaminedsufficientlybig(11).Theauthorsarecautiousintheinterpretationoftheirfindings.Ihavenoothercomments. Reviewer#2:Thisisanimportantstudyandtheresultsarepotentiallyverytimelyandmeaningful.Itisaverycarefullydonemeta-analysis.TheyshowconvincinglythattheEuropeanGWASpositiveSNPisofmuchsmallerifofnoriskeffectinChinesesamples.TheproblemwiththisstudyisthatwhiletheyshowthatthisSNPisnotassociatedwithriskatanacceptablelevelofsignificance,theydonotshowthat**isnotariskassociatedgeneinthesesamples.AsthereareotherSNPsthathaveshownassociationinothersamplestoriskandtoexpressionofthegene,forthisstudytobereallyconclusive.theyshouldalsolookatothergenotypesofinterestinthisgene,atleasttotheextentthatthereareotherSNPsthathavebeengenotypedinthesesamples.IftherearenotenoughstudieswithothertypedSNPs,thenthisshouldbenotedandexplained. Reviewer#3:Thisisafinemeta-analysis.But,theadditionaldataproducedresultsverysimilartowhattheauthorshavealreadypublishedinAJMG2012,whichconcluded"Here,westudiedrs1234andschizophreniasusceptibilityinmultipleAsiancase-controlsamples(10Chineseand2Japanesesamples;N?=?21,062),andthemeta-analysesindicatednon-significantassociationofrs1234withschizophrenia(P?=?0.26),suggestingthesameSNPidentifiedinEuropeansamplesisnotpredisposingriskinAsians."Ididnotseemuchnewinformationfromthisstudy. 面对第三个审稿人的意见,我们也很无奈,这是一个update的meta-analysis,但是审稿人揪住这一点提问,拒稿也很正常,只能改投我们随后将文章重投回schizophreniabulletin,但是这次主编没有选择送审,并提出: Onesenioreditornotes:"Recommendrejectionbecause(i)ChinesemetaanalysissampleissmallerthantheCaucasiansamples,(ii)itstillfindsasuggestivetrendforassociation,(iii)thisassociationhasbeensupersededbyrecentGWASstudies,reducinginterestinthisgene." 其实关于这个SNP的分析在我们之前的文章中已经包含过一次,并且包含了该基因的其它SNP(fine-mappinganalysis),样本量超过10000份,但是因为整体是一个negative结果,所以在投稿时屡屡被拒,最后只投到3分多的杂志上,审稿人不断提出我们的样本量没有欧洲的分析样本量大,虽然我们做了power分析(>80%),要知道,欧洲和美国的研究小组组成了一个consortium,几十个国家的样本,超过了50000份,所以审稿人屡屡说我们的样本没达到50000份,虽然我们在文章中做了很详细的解释并且提出了可能的原因,但是仍然无效,真是无奈啊前两天,我的导师要将该文章投到JournalofMedicalGenetics,我对此并不乐观,因为我感觉JMG的主编对psychiatry遗传学研究尤其是中国人群的研究存在偏见,果不其然,不超过3天就编辑部拒稿了,但是JMG杂志的投稿状态很有意思,投稿状态的变化是witheditor---awaitingreviewerselection---awaitingEICdecision---rejectedwithoutreview,状态显示是在等待选择审稿人,但是其实这只是杂志社一个状态的自动变化,只有出现awaitingreviewerassignment---underreview才表明已经送外审了今天,我的导师问我这篇文章投哪里,确实是有点累了,在我毕业之前这篇文章可能没有希望接收了,我跟我的导师说不行就投PLOSONE吧,虽然它的影响因子可能会跌破4目前,国际商务专业已横跨四个年级,拥有来自44个国家和地区的116名学生深成指2019年走势图A股市场的强势反弹与年内市场改革密切相关国内方面,科创板开板、创业板借壳松绑、分拆上市新规年底正式落地等改革不断落实;国际方面,MISCI扩容“三步走”顺利推进、沪伦通6月份正式开通、A股纳入富时罗素指数6月份正式生效等步伐不断

走求学之路不是万能的,但是不走求学之路是万万不能的ldquo不知礼,无以立dquo两千年前就有人知道这个真理了,如果现在还有人不能理解,那么这种人就太难让人理解了求学并不只是为了求成,但之所以学,就是为了学有所成试问又是有谁愿意用这青春花季来在思维的煎煞之中熬而不去快乐地享受呢?学重在学的过程,但若你不能在学的过程中有所领悟,就无所谓的成,简单的说就是学不成校党委委员,各基层党委(党总支)书记,各学院(部)党政主要负责人、机关各部门主要负责人参加学习(作者:王渊;李万银)(图文)我校举行第四届“十佳班级”评选答辩会-安徽工业大学新闻网11月27日下午,校第四届“十佳班级”评选答辩会在秀山校区新大学生活动中心报告厅举行,历时一学年的“十佳百优”班级申报、创建、展示、评比工作落下帷幕经各学院答辩推荐,18个候选班级从全校“百优班级”中脱颖而出,电气学院自动化卓越工程师141班等10个班级荣获校第四届“十佳班级”荣誉称号来自校党委宣传部、学工部(处)、学校办公室、组织部、教务处、后勤处和校团委等部门相关负责人和老师出席答辩会并担任评委,校园观察团成员应邀担任学生评委风采展示创建成果异彩纷呈自2015年开始,候选班级创建成果展示已成为“十佳班级”评选答辩特色之一,11月初,在新大学生活动中心一楼展厅的“十佳班级”创建成果展示活动吸引了不少同学驻足观看一幅幅生动的班级照片,一帧帧精彩的活动剪影,一张张闪耀的荣誉证书,展现了各候选班级在创建过程中形成的浓厚学风和优良班风,彰显着一学年来扎实的创建成效